Hyperproduction of taxol from Aspergillus fumigatus, an
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Hyperproduction of taxol from Aspergillus fumigatus, an.

Hyper-production of taxol from Aspergillus fumigatus, an ...

Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region Biotechnol Rep (Amst). 2019 Nov

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Hyper-production of taxol from Aspergillus fumigatus, an ...

Dec 01, 2019  A novel taxol-producing A. fumigatus strain explored from the Northern Himalayan region.. dbat and ITS genes were used as molecular markers for screening and

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Hyper-production of taxol from Aspergillus fumigatus, an ...

Nov 15, 2019  Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region Pradeep Kumar , a, b, 1 Balwant

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(PDF) Hyper-production of Taxol from Aspergillus fumigatus ...

Hyper-production of Taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region November 2019 Biotechnology Reports

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Hyper-production of taxol from Aspergillus fumigatus, an ...

Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region Pradeep a Kumara,b,1, Balwant

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[Isolation and identification of a taxol-producing ...

May 01, 2008  Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region. Kumar P, Singh B, Thakur V, Thakur

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Taxol Determination From Pestalotiopsis Pauciseta, a ...

Taxol is the most effective antitumor agent developed in the past three decades. It has been used for effective treatment of a variety of cancers. A taxol-producing

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Semi-continuous production of the anticancer drug taxol by ...

Jan 30, 2020  Taxol is the most profitable drug ever developed in cancer chemotherapy; however, the market demand for the drug greatly exceeds the supply that can be sustained

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Biotechnology Reports Endophytes in biotechnology – the ...

Apr 11, 2021  Since the times of early civilizations, plant metabolites have been used as drugs, fragrances, flavoring agents, insecticides, stimulants, dyes, etc. However, due to the

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Aspergillus fumigatus - Wikipedia

Aspergillus fumigatus is a species of fungus in the genus Aspergillus, and is one of the most common Aspergillus species to cause disease in individuals with an immunodeficiency. Aspergillus fumigatus, a saprotroph widespread in nature, is typically found in soil and decaying organic matter, such as compost heaps, where it plays an essential role in

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[Isolation and identification of a taxol-producing ...

May 01, 2008  Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region. Kumar P, Singh B, Thakur V, Thakur A, Thakur N, Pandey D, Chand D. Biotechnol Rep (Amst), 24:e00395, 15 Nov 2019

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Taxol production from Pestalotiopsis sp an endophytic ...

Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region P. Kumar , Balwant Singh , +4 authors D. Chand Biology, Medicine

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First total synthesis of taxol. 2. Completion of the C and ...

Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan region. ... Salicylic acid as an effective elicitor for improved taxol production in endophytic fungus Pestalotiopsis microspora. ... Sterol inhibitor “Fluconazole” enhance the Taxol yield and molecular expression of ...

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Taxol Producing Fungal Endophyte Colletotrichum

on the presence of dbatgene, essential for the taxol biosynthetic pathway. A fungal isolate TPF-06 was screened to be a taxol-producing strain based on the PCR amplification results. It was characterized and identified as Aspergillus fumigatusby 18S rRNA(Accession No. KU-837249). Hyper-production of taxol from Aspergillus fumigatus, an...

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Notices - AIIMS

Oct 14, 2020  Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from ... Hyperproduction of tannin acylhydrolase in submerged fermentation from Aspergillus fumigatus. J Adv Microbiol; 3(2): 60-77 (ISSN Online: 2349-7785) ...

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Aspergillus fumigatus and Aspergillosis

Aspergillus fumigatus is a saprophytic fungus that plays an essential role in recycling environmental carbon and nitrogen (235, 506, 676).Its natural ecological niche is the soil, wherein it survives and grows on organic debris. Although this species is not the most prevalent fungus in the world, it is one of the most ubiquitous of those with airborne conidia (443, 444, 466).

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Aspergillus fumigatus and aspergillosis: From basics to ...

May 10, 2021  The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by causing numerous invasive infections and a notable mortality in humans, especially in immunocompromised patients. Mould-active azoles are the frontline therapeutics employed to treat aspergillosis. The global emergence of azole-resistant A.fumigatus isolates in clinic and environment,

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Endophytic Microbial Diversity: A New Hope for the ...

Mar 16, 2021  Taxol generated by fungal endophyte Aspergillus fumigatus through the microbial fermentation techniques was found to be 1.60 g/L, which according to the reported research is the maximum amount of taxol production to date ... Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern ...

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Aspergillus niger var. taxi, a new species variant of ...

Sep 10, 2009  The endophytic fungus Aspergillus niger from Taxus spp. has never been reported to be able to produce taxol. Our present study is the first report for the isolation, characterization and identification of a new variant of the Aspergillus niger from Taxus cuspidata in China that is able to produce taxol at a high amount of 27346 μ g l −1 .

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Bronchiectasis and Aspergillus: How are they linked ...

However, it is also possible that Aspergillus proteases in normal (or asthmatic/COPD) airways in susceptible individuals drive airway inflammation toward frank bronchiectasis through upregulating mucus production and/or driving a Th2 phenotype (see model 1 in Fig. 1). 29, 32 It is also notable that some patients with bronchiectasis have an ...

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Effects of immobilization by entrapment in alginate and ...

Feb 04, 2005  El-Sayed R. El-Sayed, Ashraf S. Ahmed, Ismail A. Hassan, Ahmed A. Ismaiel, Al-Zahraa A. Karam El-Din, Semi-continuous production of the anticancer drug taxol by Aspergillus fumigatus and Alternaria tenuissima immobilized in calcium alginate beads, Bioprocess and Biosystems Engineering, 10.1007/s00449-020-02295-8, (2020).

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Aspergillus niger var. taxi, a new species variant of ...

DOI: 10.1111/j.1365-2672.2009.04305.x Corpus ID: 5259716. Aspergillus niger var. taxi, a new species variant of taxol‐producing fungus isolated from Taxus cuspidata in China @article{Zhao2009AspergillusNV, title={Aspergillus niger var. taxi, a new species variant of taxol‐producing fungus isolated from Taxus cuspidata in China}, author={K. Zhao and W. Ping and Q.

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Pectinase and polygalacturonase production by a ...

The isolate was identified as Aspergillus fumigatus Fres. MTCC 4163. This culture was used for optimization of pectinase production using solid substrate culturing. Production of pectinase and PG by A. fumigatus. The production profile of pectinase and PG on pectin containing basal medium without sucrose was studied .

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Metabolic engineering of sesquiterpene metabolism in yeast ...

Sep 29, 2006  Efficient coupling of terpene production with hydroxylation was also demonstrated by coordinate expression of terpene hydroxylase activity, yielding 50 mg/L each of hydrocarbon and hydroxylated products. ... Duni Chand, Hyper-production of Taxol from Aspergillus fumigatus, an endophytic fungus isolated from Taxus sp. of the Northern Himalayan ...

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Notices - AIIMS

Oct 14, 2020  Hyper-production of taxol from Aspergillus fumigatus, an endophytic fungus isolated from ... Hyperproduction of tannin acylhydrolase in submerged fermentation from Aspergillus fumigatus. J Adv Microbiol; 3(2): 60-77 (ISSN Online: 2349-7785) ...

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Taxol Producing Fungal Endophyte Colletotrichum

Hyper-production of taxol from Aspergillus fumigatus, an ... In this study, we have used the gene encoding for taxadiene synthase (ts) as a molecular marker to screen the fungus (Colletotrichum capsici) for taxol production. Presently, most of the available reports support the synthesis of taxol by the fungal endophytes, and only limited ...

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Aspergillus fumigatus and aspergillosis: From basics to ...

May 10, 2021  The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by causing numerous invasive infections and a notable mortality in humans, especially in immunocompromised patients. Mould-active azoles are the frontline therapeutics employed to treat aspergillosis. The global emergence of azole-resistant A.fumigatus isolates in clinic and environment,

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Comparative transcriptome analysis of a taxol-producing ...

Jun 29, 2020  Taxol is a rare but extremely effective antitumor agent extracted from Taxus yew barks. Taxus plants are valuable and rare species, and the production of taxol from

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Frontiers The Interface between Fungal Biofilms and ...

Matrix Production. Aspergillus fumigatus produces a unique extracellular matrix during biofilm growth in vitro and in vivo (4, 18, 107). By biochemical analysis, this material consists of 40% protein, 43% carbohydrates, 14% lipids, and 3% aromatic-containing compounds, as well as DNA (108–110). The polysaccharides of the extracellular matrix ...

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Characterization of Aspergillus fumigatus Isolates from ...

Oct 26, 2016  Among airborne fungi, Aspergillus fumigatus is the most frequently encountered agent of pulmonary complications and invasive infections, as infections can result in invasive aspergillosis (IA) in immunocompromised populations, with average mortality rates

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Aspergillus Galactosaminogalactan Mediates Adherence to ...

Aug 22, 2013  Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The mechanisms underlying the adherence of this mold to host cells and macromolecules have remained elusive. Using mutants with different adhesive properties and comparative transcriptomics, we discovered that the gene uge3, encoding a fungal epimerase, is required for adherence through mediating the

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Pathophysiological aspects of Aspergillus colonization in ...

Aspergillus colonisation in Invasive Aspergillosis. Invasive aspergillosis (IA) is an opportunistic fungal infection in which lung tissue invasion by A. fumigatus or other species occurs. 6 IA is a growing health concern due to the broad and increasing range of susceptible patients, insensitivity of diagnostic testing and high mortality that can reach 94%. 22–24 The highest risk patient ...

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Biodiversity of the Genus Aspergillus in Different ...

Jan 01, 2016  Mycobiota of the northern part of the Negev desert (Rayss and Borut, 1958, Borut, 1960, Guiraud et al., 1995, Steiman et al., 1995) represented by 159 species belonging to 58 genera in which 16 of them under genus Aspergillus. Aspergillus fumigatus, Aspergillus sclerotiorum, and A. versicolor are the most common species in this region.

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In vitro effects of photodynamic therapy on Aspergillus ...

Jul 01, 2001  Abstract. Photodynamic therapy is a technique for killing cells with visible light after pretreatment with a photosensitizing agent. We demonstrated significant in vitro fungicidal activity against Aspergillus fumigatus of the photosensitizer Green 2W, activated with 630 nm light. This effect was both inoculum- and light dose-dependent.

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Production of Pyomelanin, a Second Type of Melanin, via ...

Dec 17, 2020  Aspergillus fumigatus is the most important airborne fungal pathogen of immunosuppressed humans. A. fumigatus is able to produce dihydroxynaphthalene melanin, which is predominantly present in the conidia. Its biosynthesis is an important virulence determinant. Here, we show that A. fumigatus is able to produce an alternative melanin, i.e., pyomelanin, by a different

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Aspergillosis: Practice Essentials, Background ...

May 12, 2021  Aspergillus hyphae are histologically distinct from other fungi in that the hyphae have frequent septae, which branch at 45° angles. The hyphae are best visualized in tissue with silver stains. Although many species of Aspergillus have been isolated in nature, A fumigatus is the most common cause of infection in humans.A flavus and A niger are less common.

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Immunotherapy of aspergillosis - UMinho

Aspergillus fumigatus is a ubiquitous mould that can adapt to a broad range of environmental conditions [1]. A. fumigatus can cause a number of diseases ranging from allergic to invasive, life-threatening forms of infection, which are strictly defined by the immune status of the host.

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(PDF) Single infusion of myeloid progenitors reduces death ...

The myeloid progenitors were infused 30 hours after 5-FU administration and the mice were infected 8 days after chemotherapy via intranasal instillation of A fumigatus conidia. The group that had received the CMP/GMP infusion (n ϭ 41) had a significantly higher survival rate than the group treated with 5-FU only (n ϭ 75) (56% and 33% ...

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